TY  - JOUR
TI  - Benefits of platelet rich plasma (PRP) treatment on skin autografts and allografts in a burned patient
AU  - Maciuceanu-Zarnescu, Mircea Bogdan
AU  - Grosu-Bularda, Andreea
AU  - Cretu, Andrei
AU  - Chiotoroiu, Alexandru Laurentiu
AU  - Lascar, Ioan
AU  - Mihai, Carmen
T2  - Industria Textila
AB  - Wound healing is promoted by a series of growth factors, secreted from the alpha granules of the platelets. Platelet rich
plasma (PRP) emerged as a clinical strategy to increase the physiologic concentration of platelets and its clinical use
for a large spectrum of disorders is reported, with good results. Extensive burns represent a promising field for PRP use,
those patients confronting challenging wound healing and poor long-term results. We present our initial clinical
experience represented by a case of a 51-year-old male patient, severely burned, who benefited from sequential
surgical treatment of deep burn wound excisions and coverage using autologous and allogenic skin grafts. PRP was
added to this patient’s therapy in two stages, being injected and externally applied on the autografts in functional areas
of the hands and the right upper arm region where both autografts and allografts were placed, with the exciting result of
promoting allograft integration, long-term persistence and healing. Several literature data validate successful clinical
applications of PRP in various therapies, including treatment of soft tissue injuries and chronic wounds, orthopedic
surgery, burns, maxillo-facial surgery and elaboration of tissue-engineered products. Based on our preliminary
experience and favourable reports in the literature, we encourage wider use of platelet rich plasma for
immunomodulation and tissue-engineered constructs, due to its effects on local inflammatory response and role in
enhancing the integration of various types of tissue grafts.
DA  - 2023/08/30/
PY  - 2023
DO  - 10.35530/IT.074.04.2021114
DP  - DOI.org (Crossref)
VL  - 74
IS  - 04
SP  - 470
EP  - 478
SN  - 12225347
UR  - http://revistaindustriatextila.ro/images/2023/4/013%20MIRCEA%20BOGDAN%20MACIUCEANU-ZARNESCU%20INDUSTRIA%20TEXTILA%20no.4_2023.pdf
Y2  - 2023/09/03/15:54:15
ER  -